Raoul Tibes : rechercher sur Z-Library

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1

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

Von Hoff, Daniel D., LoRusso, Patricia M., Rudin, Charles M., Reddy, Josina C., Yauch, Robert L., Tibes, Raoul, Weiss, Glen J., Borad, Mitesh J., Hann, Christine L., Brahmer, Julie R., Mackey, Howard

Journal:

Boston Medical and Surgical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 654 KB

english, 2009

2

Hedgehog antagonist GDC-0449 is effective in the treatment of advanced basal cell carcinoma

Shivan H. Amin, Raoul Tibes, Ji-Eon Kim, C. Patrick Hybarger

Journal:

The Laryngoscope

Année:

2010

Langue:

english

Fichier:

PDF, 149 KB

english, 2010

3

TYROSINE KINASE INHIBITORS AND THE DAWN OF MOLECULAR CANCER THERAPEUTICS*

Tibes, Raoul, Trent, Jonathan, Kurzrock, Razelle

Journal:

Annual Review of Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 616 KB

english, 2005

4

Activity of alemtuzumab in patients with CD52-positive acute leukemia

Raoul Tibes, Michael J. Keating, Alessandra Ferrajoli, William Wierda, Farhad Ravandi, Guillermo Garcia-Manero, Susan O'Brien, Jorge Cortes, Srdan Verstovsek, Mary L. Browning, Stefan Faderl

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 85 KB

english, 2006

5

Patient willingness to undergo pharmacodynamic and pharmacokinetic tests in early phase oncology trials

Raoul Tibes, Barbara F. Piper, Jessica A. Smith, Raysenia L. James, Martin A. Benjamin, Jay H. Yim, Ramesh K. Ramanathan, Daniel D. Von Hoff, R. Curtis Bay, Mitesh J. Borad

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 145 KB

english, 2011

6

Transformation of a Chronic Myeloproliferative Neoplasm to Acute Myelogenous Leukemia: Does Anything Work?

Madappa N. Kundranda, Raoul Tibes, Ruben A. Mesa

Journal:

Current Hematologic Malignancy Reports

Année:

2012

Langue:

english

Fichier:

PDF, 242 KB

english, 2012

7

PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation

Raoul Tibes, Steven M. Kornblau, Yihua Qiu, Spyro M. Mousses, Christiane Robbins, Tracy Moses, John D. Carpten

Journal:

British Journal of Haematology

Année:

2008

Langue:

english

Fichier:

PDF, 103 KB

english, 2008

8

Evolution of clinical trial endpoints in chronic myeloid leukemia: Efficacious therapies require sensitive monitoring techniques

Raoul Tibes, Ruben A. Mesa

Journal:

Leukemia Research

Année:

2012

Langue:

english

Fichier:

PDF, 486 KB

english, 2012

9

RNAi screening of the kinome identifies modulators of cisplatin response in ovarian cancer cells

Shilpi Arora, Kristen M. Bisanz, Lourdes A. Peralta, Gargi D. Basu, Ashish Choudhary, Raoul Tibes, David O. Azorsa

Journal:

Gynecologic Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 957 KB

english, 2010

10

18-FDG PET/CT assessment of basal cell carcinoma with vismodegib

Curtis A. Thacker, Glen J. Weiss, Raoul Tibes, Lisa Blaydorn, Molly Downhour, Erica White, Jason Baldwin, Daniel D. Von Hoff, Ronald L. Korn

Journal:

Cancer Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2012

11

Myeloproliferative neoplasms 5 years after discovery of JAK2V617F: what is the impact of JAK2 inhibitor therapy?

Tibes, Raoul, Mesa, Ruben A.

Journal:

Leukemia and Lymphoma

Année:

2011

Langue:

english

Fichier:

PDF, 209 KB

english, 2011

12

Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies

Glen J. Weiss, Manuel Hidalgo, Mitesh J. Borad, Daniel Laheru, Raoul Tibes, Ramesh K. Ramanathan, Lisa Blaydorn, Gayle Jameson, Antonio Jimeno, Jeffrey D. Isaacs, Angela Scaburri, Maria Adele Pacciari

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 393 KB

english, 2012

13

MPN blast phase: Clinical challenge and assessing response

Ruben A. Mesa, Raoul Tibes

Journal:

Leukemia Research

Année:

2012

Langue:

english

Fichier:

PDF, 82 KB

english, 2012

14

RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma

Shilpi Arora, Irma M Gonzales, R Tanner Hagelstrom, Christian Beaudry, Ashish Choudhary, Chao Sima, Raoul Tibes, Spyro Mousses, David O Azorsa

Journal:

Molecular Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 3.08 MB

english, 2010

15

Phase I trial of UNBS5162, a novel naphthalimide in patients with advanced solid tumors or lymphoma

Mahadevan, Daruka, Northfelt, Donald W., Chalasani, Pavani, Rensvold, Diane, Kurtin, Sandra, Hoff, Daniel D., Borad, Mitesh J., Tibes, Raoul

Journal:

International Journal of Clinical Oncology

Année:

2013

Langue:

english

Fichier:

PDF, 424 KB

english, 2013

16

Current Outlook on Molecular Pathogenesis and Treatment of Myeloproliferative Neoplasms

Tibes, Raoul, Bogenberger, James M., Benson, Kasey L., Mesa, Ruben A.

Journal:

Molecular Diagnosis & Therapy

Année:

2012

Langue:

english

Fichier:

PDF, 467 KB

english, 2012

17

A phase I, first-in-human dose-escalation study of amuvatinib, a multi-targeted tyrosine kinase inhibitor, in patients with advanced solid tumors

Raoul Tibes, Gil Fine, Gavin Choy, Sanjeev Redkar…

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 232 KB

english, 2013

18

Effect of selection of QTc formula on eligibility of cancer patients for phase I clinical trials

Mitesh J. Borad, Arundhati D. Soman, Martin Benjamin, Daniel Casa, Waibhav D. Tembe, Barbara F. Piper, Ramesh Ramanathan, Raoul Tibes, Gayle Jameson, Karen Ansaldo, Daniel D. Von Hoff…show all 11hide

Journal:

Investigational New Drugs

Année:

2013

Langue:

english

Fichier:

PDF, 298 KB

english, 2013

19

Central Nervous System Leukemia in Acute Myeloid Leukemia

Altriki, Mohamad, Cheng, Meng-Ru, Fauble, Veena, Khera, Nandita, Leis, Jose, Mesa, Ruben A., Noel, Pierre, Slack, James L., Tibes, Raoul, Sproat, Lisa Ostrosky

Journal:

Biology of Blood and Marrow Transplantation

Année:

2014

Langue:

english

Fichier:

PDF, 47 KB

english, 2014

20

Usefulness of 3 Monthly Marrow Evaluations in Predicting Relapse of Myeloid Malignancies After HCT

Kelemen, Katalin, Fauble, Veena, Sproat, Lisa Ostrosky, Leis, Jose, Noel, Pierre, Klein, Jared, Tibes, Raoul, Slack, James, Adams, Roberta, Mesa, Ruben, Khera, Nandita

Journal:

Biology of Blood and Marrow Transplantation

Année:

2013

Langue:

english

Fichier:

PDF, 74 KB

english, 2013

21

Emerging drugs for polycythemia vera

Tibes, Raoul, Mesa, Ruben A

Journal:

Expert Opinion on Emerging Drugs

Année:

2013

Langue:

english

Fichier:

PDF, 373 KB

english, 2013

22

Targeting hedgehog signaling in myelofibrosis and other hematologic malignancies

Tibes, Raoul, Mesa, Ruben A

Journal:

Journal of Hematology & Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 526 KB

english, 2014

23

Phase I dose-escalation studies of SNX-5422, an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumours

Infante, Jeffrey R., Weiss, Glen J., Jones, Suzanne, Tibes, Raoul, Bauer, Todd M., Bendell, Johanna C., Hinson, James M., Von Hoff, Daniel D., Burris, Howard A., Orlemans, Everardus O., Ramanathan, Ra

Journal:

European Journal of Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 863 KB

english, 2014

24

Chk1 and WEE1 Inhibition Combine Synergistically and Represent a Novel Non-cytotoxic Combination in Acute Myeloid Leukemia

Tibes, Raoul, Chaudhuri, Leena, Vincelette, Nicole D., Kohl, Brian D., Naylor, Ryan M., Flatten, Karen S., Peterson, Kevin L., McNally, Amanda, Gojo, Ivana, Karp, Judith E., Mesa, Ruben A., Sproat, Li

Journal:

Clinical Lymphoma Myeloma and Leukemia

Année:

2014

Langue:

english

Fichier:

PDF, 141 KB

english, 2014

25

JAK inhibition: the key to treating myeloproliferative neoplasm?

Tibes, Raoul, Bogenberger, James M, Mesa, Ruben A

Journal:

Expert Review of Hematology

Année:

2012

Langue:

english

Fichier:

PDF, 856 KB

english, 2012

26

Phase 1 dose escalation trial of ilorasertib, a dual Aurora/VEGF receptor kinase inhibitor, in patients with hematologic malignancies

Garcia-Manero, Guillermo, Tibes, Raoul, Kadia, Tapan, Kantarjian, Hagop, Arellano, Martha, Knight, Emily A., Xiong, Hao, Qin, Qin, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Albert, Daniel

Journal:

Investigational New Drugs

Année:

2015

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2015

27

Ex vivo activity of BCL-2 family inhibitors ABT-199 and ABT-737 combined with 5-azacytidine in myeloid malignancies

Bogenberger, James M., Delman, Devora, Hansen, Nanna, Valdez, Riccardo, Fauble, Veena, Mesa, Ruben A., Tibes, Raoul

Journal:

Leukemia and Lymphoma

Année:

2015

Langue:

english

Fichier:

PDF, 670 KB

english, 2015

28

Long-term safety, tolerability, and efficacy of vismodegib in two patients with metastatic basal cell carcinoma and basal cell nevus syndrome

Weiss, Glen J., Tibes, Raoul, Blaydorn, Lisa, Jameson, Gayle, Downhour, Molly, White, Erica, Caro, Ivor, Von Hoff, Daniel D.

Journal:

Dermatology Reports

Année:

2011

Langue:

english

Fichier:

PDF, 196 KB

english, 2011

29

Ruxolitinib in clinical practice for therapy of myelofibrosis: Single USA center experience following Food and Drug Administration approval

Geyer, Holly, Cannon, Keith, Knight, Emily, Fauble, Veena, Camoriano, John, Emanuel, Robyn, Tibes, Raoul, Mesa, Ruben

Journal:

Leukemia and Lymphoma

Année:

2014

Langue:

english

Fichier:

PDF, 208 KB

english, 2014

30

Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study

Issa, Jean-Pierre J, Roboz, Gail, Rizzieri, David, Jabbour, Elias, Stock, Wendy, O'Connell, Casey, Yee, Karen, Tibes, Raoul, Griffiths, Elizabeth A, Walsh, Katherine, Daver, Naval, Chung, Woonbok, Nai

Journal:

The Lancet Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 513 KB

english, 2015

31

Epidemiology of adult acute myeloid leukemia: Impact of exposures on clinical phenotypes and outcomes after therapy

Finn, Laura, Sproat, Lisa, Heckman, Michael G., Jiang, Liuyan, Diehl, Nancy N., Ketterling, Rhett, Tibes, Raoul, Valdez, Ricardo, Foran, James

Journal:

Cancer Epidemiology

Année:

2015

Langue:

english

Fichier:

PDF, 636 KB

english, 2015

32

JAK2 inhibitors in the treatment of myeloproliferative neoplasms: rationale and clinical data

Tibes, Raoul, Mesa, Ruben

Journal:

Clinical Investigation

Année:

2011

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2011

33

The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia

Tibes, Raoul, Al-Kali, Aref, Oliver, Gavin R, Delman, Devora H, Hansen, Nanna, Bhagavatula, Keerthi, Mohan, Jayaram, Rakhshan, Fariborz, Wood, Thomas, Foran, James M., Mesa, Ruben A., Bogenberger, Jam

Journal:

Journal of Hematology & Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 936 KB

english, 2015

34

A study of high-dose lenalidomide induction and low-dose lenalidomide maintenance therapy for patients with hypomethylating agent refractory myelodysplastic syndrome

Cherian, Mathew A., Tibes, Raoul, Gao, Feng, Fletcher, Theresa, Fiala, Mark, Uy, Geoffrey L., Westervelt, Peter, Jacoby, Meagan A., Cashen, Amanda F., Stockerl-Goldstein, Keith, DiPersio, John F., Vij

Journal:

Leukemia and Lymphoma

Année:

2016

Langue:

english

Fichier:

PDF, 886 KB

english, 2016

35

Living with Cancer: an Educational Intervention in Cancer Patients Can Improve Patient-Reported Knowledge Deficit

Padrnos, Leslie, Bennett, Robert, Kosiorek, Heidi, Dueck, Amylou C., Northfelt, Donald, Mikhael, Joseph, Tibes, Raoul, Khera, Nandita, Mesa, Ruben A.

Journal:

Journal of Cancer Education

Année:

2016

Langue:

english

Fichier:

PDF, 857 KB

english, 2016

36

Guadecitabine (SGI-110) in treatment-naive patients with acute myeloid leukaemia: phase 2 results from a multicentre, randomised, phase 1/2 trial

Kantarjian, Hagop M, Roboz, Gail J, Kropf, Patricia L, Yee, Karen W L, O'Connell, Casey L, Tibes, Raoul, Walsh, Katherine J, Podoltsev, Nikolai A, Griffiths, Elizabeth A, Jabbour, Elias, Garcia-Manero

Journal:

The Lancet Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 461 KB

english, 2017

37

Randomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in relapsed and refractory acute myeloid leukemia

Webster, Jonathan A., Tibes, Raoul, Morris, Larry, Blackford, Amanda L., Litzow, Mark, Patnaik, Mrinal, Rosner, Gary L., Gojo, Ivana, Kinders, Robert, Wang, Lihua, Doyle, L. Austin, Huntoon, Catherine

Journal:

Leukemia Research

Année:

2017

Langue:

english

Fichier:

PDF, 888 KB

english, 2017

38

All Thiopurines Are Equal But Some Thiopurines Are More Equal Than Others—Reply

Tibes, Raoul, Ertz-Archambault, Nathalie, Kosiorek, Heidi

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 45 KB

english, 2017

39

A Single Center Analysis of Clofarabine Use Prior to Bone Marrow Transplantation in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Scheckel, Caleb, Betcher, Jeffrey Alan, Sproat, Lisa Z., Khera, Nandita, Slack, James L., Leis, Jose F., Noel, Pierre, Tibes, Raoul, Mi, Lanyu, Palmer, Jeanne

Journal:

Biology of Blood and Marrow Transplantation

Année:

2018

Langue:

english

Fichier:

PDF, 305 KB

english, 2018

40

Comparison of Mitoxantrone-Based Salvage Therapies (MEC vs CLAG-M) in Relapsed or Refractory Acute Myeloid Leukemia

Scheckel, Caleb, Betcher, Jeffrey Alan, Sproat, Lisa Z., Tibes, Raoul, Slack, James L., Leis, Jose F., Noel, Pierre, Mi, Lanyu, Palmer, Jeanne

Journal:

Biology of Blood and Marrow Transplantation

Année:

2018

Langue:

english

Fichier:

PDF, 412 KB

english, 2018

41

The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia

Stein, Eytan M., Garcia-Manero, Guillermo, Rizzieri, David A., Tibes, Raoul, Berdeja, Jesus G., Savona, Michael R., Jongen-Lavrenic, Mojca, Altman, Jessica K., Thomson, Blythe, Blakemore, Stephen J.,

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 635 KB

english, 2018

42

Relapse of Myeloid Neoplasms after Allogeneic Hematopoietic Cell Transplantation: Association of the Molecular Evolution with Cytogenetic Evolution

Kelemen, Katalin, Malik, Fatima, Ertz-Archambault, Natalie, Kosiorek, Heidi, Tibes, Raoul, Khera, Nandita

Journal:

Biology of Blood and Marrow Transplantation

Année:

2018

Langue:

english

Fichier:

PDF, 121 KB

english, 2018

43

Safety, pharmacokinetics, and preliminary efficacy of E6201 in patients with advanced solid tumours, including melanoma: results of a phase 1 study

Tibes, Raoul, Borad, Mitesh J., Dutcus, Corina E., Reyderman, Larisa, Feit, Kevie, Eisen, Andrew, Verbel, David A., Von Hoff, Daniel D.

Journal:

British Journal of Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 332 KB

english, 2018

44

A Multidisciplinary Biospecimen Bank of Renal Cell Carcinomas Compatible with Discovery Platforms at Mayo Clinic, Scottsdale, Arizona

Ho, Thai H., Nateras, Rafael Nunez, Yan, Huihuang, Park, Jin G., Jensen, Sally, Borges, Chad, Lee, Jeong Heon, Champion, Mia D., Tibes, Raoul, Bryce, Alan H., Carballido, Estrella M., Todd, Mark A., J

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.20 MB

english, 2015

45

Final results of a randomized multicenter phase II study of alvocidib, cytarabine, and mitoxantrone versus cytarabine and daunorubicin (7 + 3) in newly diagnosed high-risk acute myeloid leukemia (AML)

Zeidner, Joshua F., Foster, Matthew C., Blackford, Amanda L., Litzow, Mark R., Morris, Lawrence E., Strickland, Stephen A., Lancet, Jeffrey E., Bose, Prithviraj, Levy, M. Yair, Tibes, Raoul, Gojo, Iva

Journal:

Leukemia Research

Année:

2018

Langue:

english

Fichier:

PDF, 211 KB

english, 2018

46

The Impact of Concomitant Medication Use on Patient Eligibility for Phase I Cancer Clinical Trials

Borad, Mitesh J., Curtis, Kelly K., Babiker, Hani M., Benjamin, Martin, Tibes, Raoul, Ramanathan, Ramesh K., Wright, Karen, Dueck, Amylou C., Jameson, Gayle, Von Hoff, Daniel D.

Journal:

Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 580 KB

english, 2012

47

E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases

Babiker, Hani M., Byron, Sara A., Hendricks, William P. D., Elmquist, William F., Gampa, Gautham, Vondrak, Jessica, Aldrich, Jessica, Cuyugan, Lori, Adkins, Jonathan, De Luca, Valerie, Tibes, Raoul, B

Journal:

Investigational New Drugs

Année:

2018

Langue:

english

Fichier:

PDF, 2.39 MB

english, 2018

48

Triazolo[4,5-d]pyrimidines as Validated General Control Nonderepressible 2 (GCN2) Protein Kinase Inhibitors Reduce Growth of Leukemia Cells

Lough, Lea, Sherman, Dan, Beccera-Flores, Manuel, Lavinda, Olga, Ni, Eric, Wang, Hong, Tibes, Raoul, Cardozo, Timothy

Journal:

Computational and Structural Biotechnology Journal

Année:

2018

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2018

49

Recent developments in myelofibrosis

Tibes, Raoul, Bogenberger, James, Mesa, Ruben

Journal:

Blood and Lymphatic Cancer Targets and Therapy

Année:

2012

Langue:

english

Fichier:

PDF, 361 KB

english, 2012

50

Guadecitabine (SGI-110) in patients with intermediate or high-risk myelodysplastic syndromes: phase 2 results from a multicentre, open-label, randomised, phase 1/2 trial

Garcia-Manero, Guillermo, Roboz, Gail, Walsh, Katherine, Kantarjian, Hagop, Ritchie, Ellen, Kropf, Patricia, O'Connell, Casey, Tibes, Raoul, Lunin, Scott, Rosenblat, Todd, Yee, Karen, Stock, Wendy, Gr

Journal:

The Lancet Haematology

Année:

2019

Langue:

english

Fichier:

PDF, 373 KB

english, 2019